期刊简介
《国际精神病学杂志》(季刊)创刊于1974年,由教育部主管,中南大学主办,中南大学湘雅二医院承办。编辑部目前有4名专职工作人员,其中三位专职编辑均是教授,并有两位是博士生导师。
《国际精神病学杂志》是由国家新闻出版总署正式批准的医学专业性综合学术期刊。国内外公开发行,已被《中国知网》、《中文科技期刊数据库》、《中国核心期刊(遴选)数据库》、《中国学术期刊(光盘版)数据库》、《中国学术期刊综合评价数据库统计源期刊》等收录。本刊以广大临床医务工作者为读者对象,报道医疗领域内领先的科研成果和临床诊疗经验,帮助广大临床医师提高学术水平,解决在临床中遇到的具体问题。办刊宗旨:充分利用广泛的专家资源,技术资源和人力资源,科学化组织和出版医药卫生知识和相关信息,为医药卫生行业和医药卫生工作者提供交流与探索的园地,成为具有现实性和实用性的知识平台。主要刊登医学教育、科研、临床的中医、临床医学、中西医结合、公共医学、民族医药、护理、检验、医技、药学、管理等与医学相关的学术论文。
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- 杂志名称:国际精神病学杂志
- 主管单位:中华人民共和国教育部
- 主办单位:中南大学
- 国际刊号:1673-2952
- 国内刊号:43-1457/R
- 出版周期:季刊
期刊荣誉:中国期刊全文数据库(CJFD)期刊收录:国家图书馆馆藏, 知网收录(中), 统计源核心期刊(中国科技论文核心期刊), 上海图书馆馆藏, 维普收录(中)
The change of serum folic acid,homocysteine and its relationship with cognitive function in first episode schizophrenia
ZHANG Yinghui;YANG Mei;WANG Desui;HUANG Ling
关键词:schizophrenia, folic acid, Hcy, cognitive function
摘要:Objective To observe the change of serum folic acid,homocysteine (Hcy) and its relationship with cognitive function in first episode schizophrenia (SZ).Methods Forty-five patients with first episode schizophrenia treated in our hospital from March 2014 to June 2015 were selected as the observation group,and 50 healthy adults were selected as the control group.The serum level of folic acid,Hcy and cognitive function were observed in two groups.The correlation between them was analyzed by Pearson correlation analysis.Results The level of folic acid of the first episode SZ patients was significantly lower than that of the control group,while the Hcy level was significantly higher than that of the control group,and the difference was statistically significant (P< 0.05);The scores of orientation,instantaneous memory,attention,word immediate memory and delayed recall of the observation group were significantly lower than those of the control group (P<0.05);The level of folic acid was positively correlated with orientation,instantaneous memory and attention and calculation,while the Hcy level was negatively correlated with the indexes mentioned above;the folic acid,homocysteine (Hcy) level had no obvious correlation with language ability,visual and spatial perception and word immediate memory.Conclusions The level of serum folic acid of the patients with first episode SZ are lower and the level of serum Hcy is higher,and the above indexes are closely related with some cognitive functions of the patients.
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